Repercussões auditivas da síndrome alcoólica fetal

Conteúdo do artigo principal

Osmar Clayton Person
Dafne Patrícia Cerchiari
Giovana Moretti
Raul Vítor Rossi Zanini
Tatiana Alves Monteiro
Priscila Bogar Rapoport

Resumo

O abuso de álcool durante a gravidez, além de causar impacto individual, familiar e social, causa sérios danos ao recém-nascido. O álcool tem a capacidade de causar grande injúria ao embrião e ao feto, e a Síndrome Alcoólica Fetal é a manifestação mais grave desse processo. O sistema auditivo, assim como o sistema nervoso central, está vulnerável aos efeitos tóxicos do álcool devido ao período embriológico em que se forma, podendo haver deficiência auditiva em diferentes graus em crianças cujas mães fizeram uso de grandes quantidades de álcool no período gestacional. A aquisição e o desenvolvimento da linguagem dependem diretamente da função auditiva, que deve ser acompanhada em crianças acometidas por essa síndrome, destacando-se o papel de pediatras, neurologistas e otorrinolaringologistas nesse processo. O presente trabalho descreve quatro casos de Síndrome Alcoólica Fetal (SAF) e aborda aspectos clínicos e epidemiológicos relevantes dessa síndrome, enfatizando as repercussões auditivas, que têm tido pouco enfoque na literatura científica mundial.

Downloads

Não há dados estatísticos.

Detalhes do artigo

Seção
Artigos

Referências

Armant DR, Saunders DE. Exposure of embryonic cells to alcohol: contrasting effects during preimplantation and postimplantation development. Seminars in Perinatology, New York 1996; 20(2): 127-39. http://dx.doi.org/10.1016/S0146-0005(96)80080-2

Corrêa CL, Ferreira MG, Lemonica IP. Consumo de álcool e gravidez: riscos decorrentes desta associação. Revista Brasileira de Toxicologia 2000; 13(1): 5-10.

Jones KL, Smith DW. Recognition of the fetal alcohol syndrome in early infancy. Lancet 1973; 2: 999-1001. http://dx.doi.org/10.1016/S0140-6736(73)91092-1

Sampson PD, Streissguth AP, Bookstein FL, Little RE, Clarren SK, Dehaene P, Hanson JW, Graham JM. Incidence of fetal alcohol syndrome and prevalence of alcohol- related neurodevelopmental disorder. Teratology 1997; 56: 317-26. http://dx.doi.org/10.1002/(SICI)1096-9926(199711)56:5<317::AID-TERA5>3.0.CO;2-U

Obregón MG, Torrado MV. El alcohol en la gestación. Arch Arg Pediatr 1996; 94: 107- 110.

Spagnolo A. Teratogenesis of alcohol. Ann Ist Super Sanità 1993; 29(1): 89-96.

Church MW, Abel EL, Kaltenbach JA, Overbeck GW. Effects of prenatal alcohol exposure and aging on auditory function in the rat: preliminary results. Alcoholism: Clinical and Experimental Research 1996; 20(1): 172-79. http://dx.doi.org/10.1111/j.1530-0277.1996.tb01061.x

Kotch LE, Sulik KK. Patterns of ethanol-induced cell death in the developing nervous system of mice; neural fold states through the time of anterior neural tube closure. Int J Dev Neurosci 1992; 10: 273-79. http://dx.doi.org/10.1016/0736-5748(92)90016-S

Nordemar H. Alcohol and ultrastructural changes in the developing inner ear. Acta Otolaryngol 1988; 105: 75-81. http://dx.doi.org/10.3109/00016488809119448

Church MW, Eldis F. Hearing disorders in children with fetal alcohol syndrome: findings from case reports. Pediatr 1988; 82:147-54.

Church MW, Kaltenbach JA. Hearing, speech, language, and vestibular disorders in the Fetal alcohol syndrome: a literature review. Alcoholism: Clinical and Experimental Research 1997; 21(3): 495-512.

Church MW, Holloway JA. The effects of prenatal alcohol exposure on postnatal development of the brainstem auditory evoked potential in rat. Alcohol Clin Exp Res 1984; 8: 258-63. http://dx.doi.org/10.1111/j.1530-0277.1984.tb05507.x

Vingan RD, Dow-Edwards DL, Riley EP. Cerebral metabolic alterations in rats following prenatal alcohol exposure: a deoxyglucose study. Alcohol Clin Exp Res 1986; 10: 22-26. http://dx.doi.org/10.1111/j.1530-0277.1986.tb05607.x

Majewski F. Die Alkoholembryopathie. Eine häufige und vermeidbare Schädigung bei Kindern. Der Kinderarzt 1986; 8:1127-38.

Rössig C, Wässer S, Oppermann P. Audiologic manifestations in fetal alcohol syndrome assessed by Brainstem Auditory-Evoked Potentials. Neuropediatrics 1994; 25: 245-49. http://dx.doi.org/10.1055/s-2008-1073029

Church MW, Eldis F, Blakley BW, Bawle EV. Hearing, speech, language, vestibular and dentofacial disorders in the Fetal Alcohol Syndrome (FAS). Alcohol Clin Exp Res 1997; 21: 227-37. http://dx.doi.org/10.1111/j.1530-0277.1997.tb03754.x

Becker M, Warr-Leeper GA, Leeper HA. Fetal alcohol syndrome: a description of oral motor, articulatory, short-term memory, grammatical, and semantic abilities. J Commun Disord 1990; 23: 97-124. http://dx.doi.org/10.1016/0021-9924(90)90016-R

Iosub S, Fuchs M, Bingol N, Gromisch DS. Fetal alcohol syndrome revisited. Pediatrics 1981; 68: 475-79.

Figueiredo MS, Castro Jr NP. Potenciais evocados auditivos precoces. In: Tratado de Otorrinolaringologia, Sociedade Brasileira de Otorrinolaringologia–São Paulo: Roca, 2002; vol 1, cap 42: p. 522-29.

Mesquita MA. Síndrome alcoólica fetal. Einstein 2003; 1(2):146.

Bluestone CD. Diseases and disorders of the eustachian tube middle ear. In: Paparella MM, Shumrick DA, Gluckman JL, Meyer WL. Otolaryngology, vol 2, 3rd ed. Philadelphia, Saunders; 1991: 1289-1315.

Lewis PD. Neuropathological effects of alcohol on the developing nervous system. Alcohol 1985; 20:195-200.

Church MW. Chronic in utero alcohol exposure affects auditory function in rats and in humans. Alcohol 1987; 4:231-39. http://dx.doi.org/10.1016/0741-8329(87)90017-6

Lewis N. Otitis media and linguistic incompetence. Arch Otolaryngol 1976; 102: 387-90. http://dx.doi.org/10.1001/archotol.1976.00780120035001

Wekselman K, Spiering K, Hetteberg C, Kenner C, Flandermeyer A. Fetal alcohol syndrome from infancy through childhood: a review of the literature. Journal of Pediatric Nursing 1995; 10(5):296-303. http://dx.doi.org/10.1016/S0882-5963(05)80047-8